Quick answer — what's actually worth taking

Strong evidence: Hydrolysed collagen + vitamin C (before exercise), omega-3s (EPA/DHA), creatine monohydrate, HMB (during immobilisation).

Worth taking if deficient: Vitamin D, magnesium.

Plausible, low risk: Curcumin with piperine, zinc, vitamin C (standalone).

Not worth the cost: Bromelain, glucosamine, proprietary "tendon repair" blends, most branded recovery supplements.

How to Read This Page

Each supplement is rated on a five-dot evidence scale and assigned one of three verdicts. Strong evidence means multiple RCTs or systematic reviews support the intervention for this specific use case. Plausible means the mechanism is sound and some evidence supports it, but direct clinical data for Achilles recovery specifically is limited. Weak evidence means the intervention is not well-supported for this use case — either the evidence is absent, conflicting, or applies only to conditions unrelated to tendon healing.

Dose and timing matter enormously. A supplement taken incorrectly — wrong dose, wrong timing, wrong form — may produce no benefit even if the underlying evidence is strong. These details are included for each entry.

Collagen Peptides + Vitamin C

Hydrolysed Collagen + Vitamin C
Strong Evidence
Dose: 15g hydrolysed collagen + 50mg vitamin C · Timing: 60 minutes before rehabilitation exercise · Frequency: Daily
The most evidence-backed nutritional intervention specifically for tendon healing. Shaw et al. (2017) established the protocol: 15g collagen with vitamin C taken 60 minutes before exercise significantly increases collagen synthesis markers in blood. Vitamin C is a required co-factor — not optional. The timing relative to exercise is critical. Collagen without the mechanical stimulus shows a blunted response. See the full collagen page for the complete evidence breakdown.
Hydrolysed collagen peptide powder — unflavoured, at least 15g per serve. Dissolves in cold water or juice.
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Omega-3 Fatty Acids

Omega-3s (EPA + DHA)
Strong Evidence
Dose: 2–3g combined EPA+DHA daily · Timing: With a meal (fat improves absorption) · Form: Triglyceride form preferred over ethyl ester
Strong evidence for reducing systemic inflammation, supporting muscle protein synthesis during immobilisation, and blunting disuse atrophy. EPA and DHA generate anti-inflammatory resolvins and protectins that actively resolve inflammation — distinct from NSAIDs, which block inflammatory pathways. Particularly relevant during the boot phase when disuse atrophy is most aggressive. Food sources (fatty fish 3x/week) can provide meaningful amounts; supplementation is appropriate when dietary intake is inconsistent. Plant-based ALA (flaxseed, chia) does not convert efficiently to EPA/DHA — algae oil is the plant-based alternative.
Fish oil (triglyceride form, high EPA+DHA) — look for at least 1g combined EPA+DHA per capsule. Triglyceride form has better absorption than ethyl ester. Keep refrigerated.
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Creatine Monohydrate

Creatine Monohydrate
Strong Evidence
Dose: 3–5g daily · Timing: Any time — timing is not critical for this application · Loading phase: Not required
Creatine is the most extensively researched supplement in sports science and has strong evidence specifically for injury recovery contexts. During immobilisation, creatine attenuates muscle loss by supporting intracellular energy availability and osmotic signalling in muscle cells. During rehabilitation, it supports the high-intensity work — heavy calf raises, leg press, resistance training — that drives tendon remodelling. Creatine monohydrate is the form used in research. Branded alternatives (creatine HCl, Kre-Alkalyn) offer no demonstrated advantage and cost more. Mild water retention in the first 1–2 weeks is normal and not problematic.
Creatine monohydrate — the original, most-researched form. No need for fancy variants. Unflavoured powder is the most economical. 3–5g daily, no loading phase needed.
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HMB (Beta-Hydroxy Beta-Methylbutyrate)

HMB
Strong Evidence (immobilisation)
Dose: 3g daily in divided doses · Timing: With meals · Duration: Boot/immobilisation phase primarily
HMB is a metabolite of the amino acid leucine. It has specific evidence for reducing muscle protein breakdown during immobilisation — the mechanism differs from creatine and the two work well together. Multiple trials show HMB attenuates disuse atrophy in the immobilised limb, which directly affects the calf and soleus muscles critical for Achilles function. Its relevance reduces once active rehabilitation begins and mechanical loading resumes. Not as broadly useful as creatine across the full recovery arc, but during the boot phase it fills a specific gap.
HMB supplement — calcium HMB or free acid HMB are both effective forms. 3g daily in divided doses during the immobilisation phase. Combine with creatine for additive effect.
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Vitamin D

Vitamin D
Worth Checking
Dose: Depends on deficiency level — 1000–4000 IU daily is common for correction · Form: D3 (cholecalciferol) preferred over D2 · Test first if possible
Vitamin D deficiency is associated with impaired musculoskeletal healing, reduced muscle function, and increased injury risk. Correcting deficiency clearly supports recovery. However, supplementing above adequate levels when already sufficient does not appear to provide additional benefit — this is a "correct if deficient" recommendation rather than a universal one. Vitamin D deficiency is more common than most people realise, particularly in those who work indoors, live at higher latitudes, or have darker skin. A 25-OH vitamin D blood test is inexpensive and provides a clear answer. If deficient (below 50 nmol/L), supplementation is warranted. If sufficient, additional high-dose vitamin D is unlikely to help.
Vitamin D3 + K2 — D3 is more effective than D2 at raising blood levels. K2 (MK-7 form) is often paired with D3 to direct calcium appropriately. Standard 2000 IU D3 with K2 is a reasonable maintenance dose once deficiency is corrected.
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Magnesium

Magnesium
Plausible
Dose: 300–400mg daily · Form: Glycinate or malate — better tolerated than oxide · Timing: Evening (may support sleep)
Magnesium is involved in over 300 enzymatic reactions including protein synthesis, muscle function, and energy metabolism. Mild deficiency is common — estimates suggest 45–50% of the population do not meet recommended intake. Deficiency is associated with increased muscle cramps, impaired sleep, and reduced exercise performance. For Achilles recovery specifically, the evidence is mechanistic rather than direct — there are no RCTs examining magnesium and tendon healing outcomes. However, the low risk, high prevalence of deficiency, and plausible mechanisms make it a reasonable addition at low cost.
Magnesium glycinate — the glycinate form is well-absorbed and gentle on the gut compared to magnesium oxide. 300–400mg elemental magnesium daily. Particularly useful if sleep is disrupted during recovery.
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Curcumin (Turmeric)

Curcumin + Piperine
Plausible
Dose: 500–1000mg curcumin with 5mg piperine (BioPerine) · Timing: With a meal · Note: Piperine is not optional — bioavailability is severely limited without it
Curcumin is the active compound in turmeric with well-documented anti-inflammatory activity via NF-κB inhibition. The critical issue is bioavailability — standard curcumin is very poorly absorbed. Piperine (from black pepper) increases absorption by up to 2000%. Evidence for curcumin in musculoskeletal recovery is promising — multiple trials show reduced inflammatory markers and improved recovery outcomes. Direct tendon healing data is limited. The combination is low risk, relatively inexpensive, and mechanistically sound. Worth taking during the acute and remodelling phases.
Curcumin with BioPerine — piperine is essential for absorption. Without it, most curcumin passes through unabsorbed. Look for 500mg+ curcumin with at least 5mg BioPerine per serve.
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Zinc

Zinc
Plausible
Dose: 15–25mg elemental zinc daily · Form: Zinc picolinate or gluconate — better absorbed than zinc oxide · Note: Take with food; high doses long-term can deplete copper
Zinc is a cofactor in collagen synthesis and plays a role in immune function and tissue repair. Deficiency impairs wound healing. Like magnesium, zinc deficiency is more common than realised, particularly in athletes with high sweat losses. Direct evidence for zinc supplementation improving tendon healing outcomes is limited — the case is primarily mechanistic. If dietary intake is adequate (red meat, shellfish, legumes, seeds), additional supplementation is unlikely to help. If diet is restrictive or training history suggests risk of deficiency, supplementation at modest doses is low risk.

Not Worth the Cost

Bromelain
Weak Evidence
Bromelain is a proteolytic enzyme from pineapple, marketed as an anti-inflammatory and recovery aid. The evidence for its benefit in musculoskeletal injury is weak — most studies are small, poorly controlled, and not specific to tendon healing. Any anti-inflammatory effect is likely modest and inferior to omega-3s or curcumin. Not worth prioritising.
Glucosamine / Chondroitin
Weak Evidence for Tendons
Glucosamine and chondroitin are associated with cartilage health — the evidence for joints, particularly knees, is modest but exists. For tendons, which are composed of collagen rather than proteoglycans, the mechanistic case is weak. Achilles tendon recovery is a collagen remodelling problem, not a cartilage problem. These supplements are not relevant to tendon healing and should not be prioritised over the evidence-backed options above.
Proprietary "Tendon Repair" Blends
Not Recommended
A number of branded products are marketed specifically for tendon or ligament repair — typically combining several ingredients at sub-therapeutic doses. Proprietary blends obscure individual doses, making it impossible to know whether any ingredient is present in amounts supported by evidence. The premium price rarely reflects superior evidence. Build your own stack from evidence-backed individual supplements rather than paying for a branded blend.

The Priority Stack

If budget or pill fatigue requires prioritisation, here is the order that maximises evidence-to-cost value across the full recovery arc:

1
Collagen + Vitamin C
Most specific to tendon healing. Taken before rehab. Non-negotiable if you take nothing else.
2
Creatine monohydrate
Preserves muscle during immobilisation, fuels rehab. Cheap, safe, extensively researched.
3
Omega-3s (EPA+DHA)
Reduces systemic inflammation, supports muscle protein synthesis. Relevant across all phases.
4
HMB
Specific to disuse atrophy. High priority during boot phase, reduces importance post-immobilisation.
5
Vitamin D (if deficient)
Get tested. Correct if deficient. Skip if already sufficient.
6
Magnesium glycinate
Low cost, common deficiency, supports sleep and muscle function. Worth adding.
7
Curcumin + piperine
Plausible anti-inflammatory. Only effective with piperine. Good addition once 1–6 are in place.
The honest bottom line

No supplement replaces progressive mechanical loading, adequate dietary protein, and a well-structured rehabilitation programme. Supplements support the conditions for healing — they do not drive it. The first four items on the priority stack have strong evidence and should be thought of as standard of care additions to rehabilitation, not optional extras. The rest are lower priority enhancements with plausible but more limited evidence.